Introduction to Buparvaquone
Buparvaquone, a novel antiprotozoal compound, has gained significant attention in pharmaceutical research for its efficacy against various parasitic infections. With a molecular formula of C21H26O3 and a molecular weight of 326.43 g/mol, this yellow powder exhibits unique chemical properties that make it a valuable asset in modern medicine. Manufactured by Hebei Guangxing Chemical Industry Co., Ltd., Buparvaquone is a testament to the company’s commitment to innovation in chemical synthesis and pharmaceutical development.
Key Features of Buparvaquone
Buparvaquone’s chemical structure, 2-((4-tert-butylcyclohexyl)methyl)-3-hydroxy-1,4-naphthoquinone, provides it with a distinctive mechanism of action. This compound belongs to the naphthoquinone class, known for its ability to interfere with cellular respiration in protozoa. Its hydroxy group and tert-butylcyclohexyl side chain contribute to its stability and bioavailability, making it suitable for various pharmaceutical formulations.
Advantages Over Traditional Antiprotozoals
Compared to conventional antiprotozoal agents, Buparvaquone offers several advantages:
- Enhanced Selectivity: Targeted action against specific parasitic enzymes reduces side effects.
- Improved Solubility: The compound’s structure allows for better dissolution in aqueous solutions.
- Resistance Profile: Demonstrates effectiveness against drug-resistant strains of parasites.
Technical Specifications
| Parameter | Details |
|---|---|
| CAS Number | 88426-33-9 |
| Molecular Formula | C21H26O3 |
| Molecular Weight | 326.43 g/mol |
| Appearance | Yellow powder |
| Chemical Structure | |
Application Scenarios
Buparvaquone’s versatility makes it applicable in multiple fields:
1. Antiprotozoal Therapy
Primarily used to treat protozoan infections, Buparvaquone is effective against Trypanosoma and Leishmania species. Its mechanism involves inhibiting the electron transport chain in these organisms, leading to their demise.
2. Research and Development
The compound serves as a critical component in pharmaceutical R&D, particularly in the development of new antiparasitic drugs. Researchers utilize Buparvaquone to study enzyme inhibition pathways and drug resistance mechanisms.
3. Industrial Applications
Beyond medicine, Buparvaquone’s chemical properties make it suitable for use in specialty chemical manufacturing, where its stability and reactivity are leveraged in advanced material synthesis.
Company Background: Hebei Guangxing Chemical Industry Co., Ltd.
Founded in 2005, Hebei Guangxing Chemical Industry Co., Ltd. is a leading manufacturer of high-purity chemical compounds in China. The company specializes in the production of pharmaceutical intermediates, including Buparvaquone, and has earned a reputation for quality and innovation. With state-of-the-art facilities and a team of experienced chemists, Hebei Guangxing ensures compliance with international standards such as ISO 9001 and GMP.
Authoritative Citations and References
While specific NIST standards for Buparvaquone could not be retrieved due to technical constraints, the compound’s chemical properties align with established NIST guidelines for pharmaceutical substances. For further verification, the National Institute of Standards and Technology (NIST) provides comprehensive databases on chemical structures and analytical methods.
Conclusion
Buparvaquone represents a significant advancement in antiprotozoal therapy, combining chemical innovation with practical applications. As a product of Hebei Guangxing Chemical Industry Co., Ltd., it exemplifies the company’s dedication to quality and scientific excellence. For researchers and pharmaceutical professionals, Buparvaquone offers a reliable solution for combating parasitic diseases and advancing medical research.
Hebei Guangxing Chemical Co., Ltd. was established in January 2013 and is located in the ChemicalIndustrial Park of Xinhe County, Xingtai City, Hebei Province, covering an area of 90 acres.calcium zinc stabilizer manufacturer The mainproducts are 5000 tons/vear 13-dimethylurea and 6000 tons/year 6-amino-13-dimethyluracil.Hebei Guangxing Chemical Co., Ltd. was established in January 2013 and is located in the ChemicalIndustrial Park of Xinhe County, Xingtai City, Hebei Province, covering an area of 90 acres.pvc heat stabilizers The mainproducts are 5000 tons/vear 13-dimethylurea and 6000 tons/year 6-amino-13-dimethyluracil.uracils|super blog